The candidate for the postdoctoral position should be able to carry out interdisciplinary projects to study the structural and dynamic properties of Intrinsically Disordered Proteins (IDPs) and their complexes with other proteins and low weight organic compounds. Together with Prof. Mark Tester (KAUST, Desert Agriculture Initiative), we are seeking a highly motivated postdoctoral fellow with an extensive experience in the protein biochemistry and biophysical methods used for characterization of proteins and to study protein-protein/peptide interactions. The Flexible Systems research group tries to understand the physico-chemical and structural properties of disordered and largely dynamic proteins and their complexes. With this project we are focused on the protein machinery involved into the mechanisms of plant adaptation to the changing environmental conditions (i.e. salinity). To tackle this interdisciplinary task we team up with Prof. Mark Tester, the renowned plant scientist. The Salt Lab led by Prof. Mark Tester is a world leading team in plant biology and mechanisms of salinity tolerance.
Depending on the interests and skills, a candidate will have an opportunity to expand expertise in various biophysical methods relevant to state-of-the-art Integrated Structural Biology, with a particular emphasis on the solution, solid-state NMR spectroscopy and X-ray crystallography, cryo-EM, molecular dynamics simulations (MD).
Applicants should have a Ph.D. in biochemistry, chemistry, biophysics, or another relevant field. The positions require extensive experience in molecular biology, in particular with bacterial expression systems (E.coli) and purification of recombinant proteins. Good knowledge in biophysical methods used in the study of aggregation processes and spectroscopic techniques would be a clear plus. Moreover, excellent oral and written communication skills in English, effective judgment and independent problem solving, a high motivation and commitment to the academic research are expected. Additional experience in the structural biology will be regarded as an advantage.
KAUST is a new, research-only University focusing on the areas of food, water, energy and environment.
Mark Tester leads The Salt Lab (https://saltlab.kaust.edu.sa/Pages/Home.aspx), in which mechanisms of salinity tolerance are studied and the knowledge applied to deliver saltwater-based agricultural systems through the company, Red Sea Farms (https://www.redseafarms.com).